[ad_1]
Guo YS, Liu F, Hu YH, Zheng XF, Cao XP, Zhu YX, Zhang XR, Li DJ, Zhang ZH, Chen SK. Activated Plasmonic Nanoaggregates for Darkish-Area in situ imaging for HER2 protein imaging on cell surfaces. Bioconjug Chem. 2020;31:631–8.
Zhou Y, Li Q, Wu Y, Li X, Zhou Y, Wang Z, Liang H, Ding F, Hong S, Steinmetz NF, Cai H. Molecularly Stimuli-Responsive Self-assembled peptide nanoparticles for focused imaging and remedy. ACS Nano. 2023;17:8004–25.
Li C, Guo C, Fitzpatrick V, Ibrahim A, Zwierstra MJ, Hanna P, Lechtig A, Nazarian A, Lin SJ, Kaplan DL. Design of biodegradable, implantable gadgets in direction of scientific translation. Nat Opinions Mater. 2019;5:61–81.
Gupta SS, Mishra V, Mukherjee MD, Saini P, Ranjan KR. Amino acid derived biopolymers: current advances and biomedical purposes. Int J Biol Macromol. 2021;188:542–67.
Urry DW, Lengthy MM, Cox BA, Ohnishi T, Mitchell LW, Jacobs M. The artificial polypentapeptide of elastin coacervates and types filamentous aggregates. Biochim et Biophys Acta (BBA) – Protein Struct. 1974;371:597–602.
Rodriguez-Cabello JC, Gonzalez de Torre I, Ibanez-Fonseca A, Alonso M. Bioactive scaffolds based mostly on elastin-like supplies for wound therapeutic. Adv Drug Deliv Rev. 2018;129:118–33.
Urry DW, Parker TM, Reid MC, Gowda DC. Biocompatibility of the Bioelastic supplies, poly(GVGVP) and its γ-Irradiation cross-linked Matrix: Abstract of Generic Organic Take a look at outcomes. J Bioactive Suitable Polym. 1991;6:263–82.
Israeli B, Strugach DS, Gelkop S, Weber S, Gozlan DS, Amiram M. Genetically encoding light-responsive protein‐polymers utilizing translation Equipment for the Multi‐Website Incorporation of Photograph‐switchable unnatural amino acids. Adv Funct Mater. 2021;31:2011276.
Le DHT, Ibrahimova V, van den Wildenberg SAH, Wu HL, Fonseca A, Torres T, Garanger E, Leenders WPJ, Brock R, Lecommandoux S, van Hest JCM. Mild-responsive Elastin-Like peptide-based focused nanoparticles for enhanced spheroid penetration. Angewandte Chemie-Worldwide Version. 2023;62:e202300511.
Zhao Y, Singh MK, Kremer Okay, Cortes-Huerto R, Mukherji D. Why do Elastin-Like Polypeptides probably have totally different solvation behaviors in Water-Ethanol and Water-Urea mixtures? Macromolecules. 2020;53:2101–10.
Doberenz F, Zeng Okay, Willems C, Zhang Okay, Groth T. Thermoresponsive polymers and their biomedical utility in tissue engineering – a evaluate. J Mater Chem B. 2020;8:607–28.
Varanko AK, Su JC, Chilkoti A. Elastin-Like polypeptides for Biomedical Purposes. Annu Rev Biomed Eng. 2020;22:343–69.
Urry DW. Bodily Chemistry of Organic Free Power Transduction as demonstrated by Elastic protein-based polymers. J Phys Chem B. 1997;101:11007–28.
Quiroz FG, Chilkoti A. Sequence heuristics to encode part behaviour in intrinsically disordered protein polymers. Nat Mater. 2015;14:1164–71.
Holehouse AS, Pappu RV. Encoding part transitions. Nat Mater. 2015;14:1083–4.
Ludeke S, Lohner P, Stuhn LG, Betschart MU, Huber MC, Schreiber A, Schiller SM. Dynamic structural adjustments and thermodynamics in part separation processes of an intrinsically disordered-ordered protein mannequin. Angew Chem Int Ed Engl. 2022;61:e202112738.
Zong J, Cobb SL, Cameron NR. Brief elastin-like peptide-functionalized gold nanoparticles which can be temperature responsive below near-physiological circumstances. J Mater Chem B. 2018;6:6667–74.
Qin J, Sloppy JD, Kiick KL. Fantastic structural tuning of the meeting of ECM peptide conjugates by way of slight sequence modifications. Sci Adv. 2020;6:eabd3033.
Amiram M, Quiroz FG, Callahan DJ, Chilkoti A. A extremely parallel technique for synthesizing DNA repeats allows the invention of ‘sensible’ protein polymers. Nat Mater. 2011;10:141–8.
Bhattacharyya J, Bellucci JJ, Weitzhandler I, McDaniel JR, Spasojevic I, Li X, Lin C-C, Chi J-TA, Chilkoti A. A paclitaxel-loaded recombinant polypeptide nanoparticle outperforms Abraxane in a number of murine most cancers fashions. Nat Commun. 2015;6:7939.
Yang YJ, Holmberg AL, Olsen BD. Artificially Engineered protein polymers. Annu Rev Chem Biomol Eng. 2017;8:549–75.
Ibanez-Fonseca A, Flora T, Acosta S, Rodriguez-Cabello JC. Traits within the design and use of elastin-like recombinamers as biomaterials. Matrix Biol. 2019;84:111–26.
Schreiber A, Stuhn LG, Huber MC, Geissinger SE, Rao A, Schiller SM. Self-assembly toolbox of tailor-made Supramolecular architectures based mostly on an amphiphilic protein Library. Small. 2019;15:e1900163.
Martin RW, Des Soye BJ, Kwon YC, Kay J, Davis RG, Thomas PM, Majewska NI, Chen CX, Marcum RD, Weiss MG, et al. Cell-free protein synthesis from genomically recoded micro organism allows multisite incorporation of noncanonical amino acids. Nat Commun. 2018;9:1203.
Ibrahimova V, Zhao H, Ibarboure E, Garanger E, Lecommandoux S. Thermosensitive vesicles from chemically encoded lipid-grafted elastin-like polypeptides. Angew Chem Int Ed Engl. 2021;60:15036–40.
Luginbuhl KM, Mozhdehi D, Dzuricky M, Yousefpour P, Huang FC, Mayne NR, Buehne KL, Chilkoti A. Recombinant synthesis of hybrid lipid-peptide polymer fusions that Self-assemble and encapsulate hydrophobic Medicine. Angew Chem Int Ed Engl. 2017;56:13979–84.
Mozhdehi D, Luginbuhl KM, Dzuricky M, Costa SA, Xiong S, Huang FC, Lewis MM, Zelenetz SR, Colby CD, Chilkoti A. Genetically encoded cholesterol-modified polypeptides. J Am Chem Soc. 2019;141:945–51.
Meyer DE, Chilkoti A. Purification of recombinant proteins by fusion with thermally-responsive polypeptides. Nat Biotechnol. 1999;17:1112–5.
Luginbuhl KM, Schaal JL, Umstead B, Mastria EM, Li X, Banskota S, Arnold S, Feinglos M, D’Alessio D, Chilkoti A. One-week glucose management by way of zero-order launch kinetics from an injectable depot of glucagon-like peptide-1 fused to a thermosensitive biopolymer. Nat Biomed Eng. 2017;1:0078.
Banskota S, Yousefpour P, Kirmani N, Li XH, Chilkoti A. Lengthy circulating genetically encoded intrinsically disordered zwitterionic polypeptides for drug supply. Biomaterials. 2019;192:475–85.
Dzuricky M, Xiong S, Weber P, Chilkoti A. Avidity and cell uptake of integrin-targeting polypeptide Micelles is strongly shape-dependent. Nano Lett. 2019;19:6124–32.
Hsueh PY, Ju Y, Vega A, Edman MC, MacKay JA, Hamm-Alvarez SF. A multivalent ICAM-1 binding nanoparticle which inhibits ICAM-1 and LFA-1 Interplay represents a New Instrument for the investigation of autoimmune-mediated Dry Eye. Int J Mol Sci. 2020;21:2758.
Klass SH, Smith MJ, Fiala TA, Lee JP, Omole AO, Han BG, Downing KH, Kumar S, Francis MB. Self-assembling Micelles based mostly on an intrinsically disordered protein area. J Am Chem Soc. 2019;141:4291–9.
Vogele Okay, Frank T, Gasser L, Goetzfried MA, Hackl MW, Sieber SA, Simmel FC, Pirzer T. In the direction of artificial cells utilizing peptide-based response compartments. Nat Commun. 2018;9:3862.
Avila H, Truong A, Tyrpak D, Park SJ, Lei S, Li Y, Okamoto C, Hamm-Alvarez S, MacKay JA. Intracellular dynamin elastin-like polypeptides assemble into Rodlike, Spherical, and Reticular Dynasomes. Biomacromolecules. 2022;23:265–75.
Wang B, Fang H, Zhu W, Xu Y, Yang Y, Qian X. Dynamic compartmentalization of peptide-oligonucleotide conjugates with reversible nanovesicle-microdroplet part transition behaviors. ACS Appl Mater Interfaces. 2022;14:36998–7008.
Li Y, Li J, Solar J, He H, Li B, Ma C, Liu Okay, Zhang H. Bioinspired and mechanically sturdy fibers based mostly on Engineered Non-spider chimeric proteins. Angew Chem Int Ed Engl. 2020;59:8148–52.
Sugioka Y, Nakamura J, Ohtsuki C, Sugawara-Narutaki A. Thixotropic hydrogels composed of self-assembled nanofibers of double-hydrophobic elastin-like Block Polypeptides. Int J Mol Sci. 2021;22:4104.
Chambre L, Martin-Moldes Z, Parker RN, Kaplan DL. Bioengineered elastin- and silk-biomaterials for drug and gene supply. Adv Drug Deliv Rev. 2020;160:186–98.
Bahniuk MS, Alshememry AK, Elgersma SV, Unsworth LD. Self-assembly/disassembly hysteresis of nanoparticles composed of marginally soluble, quick elastin-like polypeptides. J Nanobiotechnol. 2018;16:15.
MacKay JA, Chen M, McDaniel JR, Liu W, Simnick AJ, Chilkoti A. Self-assembling chimeric polypeptide-doxorubicin conjugate nanoparticles that abolish tumours after a single injection. Nat Mater. 2009;8:993–9.
Simon JR, Carroll NJ, Rubinstein M, Chilkoti A, López GP. Programming molecular self-assembly of intrinsically disordered proteins containing sequences of low complexity. Nat Chem. 2017;9:509–15.
Wang J, Dzuricky M, Chilkoti A. The weak hyperlink: optimization of the ligand–nanoparticle interface to boost Most cancers Cell Focusing on by Polymer Micelles. Nano Lett. 2017;17:5995–6005.
Gonzalez-Obeso C, Gonzalez-Perez M, Mano JF, Alonso M, Rodriguez-Cabello JC. Complicated morphogenesis by a Mannequin intrinsically disordered protein. Small. 2020;16:e2005191.
Inostroza-Brito KE, Collin E, Siton-Mendelson O, Smith KH, Monge-Marcet A, Ferreira DS, Rodríguez RP, Alonso M, Rodríguez-Cabello JC, Reis RL, et al. Co-assembly, spatiotemporal management and morphogenesis of a hybrid protein–peptide system. Nat Chem. 2015;7:897–904.
Nelson DW, Gilbert RJ. Extracellular matrix-mimetic hydrogels for treating neural tissue Harm: a Give attention to Fibrin, Hyaluronic Acid, and Elastin-Like Polypeptide Hydrogels. Adv Healthc Mater. 2021;10:e2101329.
Vanderschuren Okay, Arranz-Gibert P, Khang M, Hadar D, Gaudin A, Yang F, Folta-Stogniew E, Saltzman WM, Amiram M, Isaacs FJ. Tuning protein half-life in mouse utilizing sequence-defined biopolymers functionalized with lipids. Proc Natl Acad Sci U S A. 2022;119:e2103099119.
Hu J, Wang G, Liu X, Gao W. Enhancing pharmacokinetics, Tumor Accumulation, and Antitumor Efficacy by Elastin-Like Polypeptide Fusion of Interferon Alpha. Adv Mater. 2015;27:7320–4.
Liang P, Wang G, Liu X, Wang Z, Wang J, Gao W. Spatiotemporal mixture of thermosensitive polypeptide fused interferon and temozolomide for post-surgical glioblastoma immunochemotherapy. Biomaterials. 2021;264:120447.
Wang Z, Guo J, Solar J, Liang P, Wei Y, Deng X, Gao W. Thermoresponsive and protease-cleavable Interferon-Polypeptide conjugates with Spatiotemporally programmed two-step launch kinetics for Tumor Remedy. Adv Sci (Weinh). 2019;6:1900586.
Park M, Vaikari VP, Lam AT, Zhang Y, MacKay JA, Alachkar H. Anti-FLT3 nanoparticles for acute Myeloid Leukemia: preclinical pharmacology and pharmacokinetics. J Management Launch. 2020;324:317–29.
Vaikari VP, Park M, Keossayan L, MacKay JA, Alachkar H. Anti-CD99 scFv-ELP nanoworms for the remedy of acute Myeloid Leukemia. Nanomedicine. 2020;29:102236.
Clements AEB, Murphy WL. Injectable biomaterials for supply of interleukin-1 receptor antagonist: towards enhancing its therapeutic impact. Acta Biomater. 2019;93:123–34.
Sarangthem V, Yi A, Kim Y, Rehemtulla A, Lee BH, Jeon YH, Singh TD, Park RW. Therapeutic impact of IL-4 receptor-targeting pro-apoptotic peptide (AP1-ELP-KLAK) in Glioblastoma Tumor Mannequin. Int J Nanomedicine. 2021;16:5039–52.
Manzari MT, Anderson GR, Lin KH, Soderquist RS, Cakir M, Zhang M, Moore CE, Skelton RN, Fevre M, Li X, et al. Genomically knowledgeable small-molecule Medicine overcome resistance to a sustained-release formulation of an engineered demise receptor agonist in patient-derived Tumor fashions. Sci Adv. 2019;5:eaaw9162.
Lee C, Peddi S, Anderson C, Su H, Cui H, Epstein AL, MacKay JA. Adaptable antibody Nanoworms designed for non-hodgkin Lymphoma. Biomaterials. 2020;262:120338.
Sreekumar PG, Li Z, Wang W, Spee C, Hinton DR, Kannan R, MacKay JA. Intra-vitreal alphaB crystallin fused to elastin-like polypeptide offers neuroprotection in a mouse mannequin of age-related macular degeneration. J Management Launch. 2018;283:94–104.
Gilroy CA, Capozzi ME, Varanko AK, Tong J, D’Alessio DA, Campbell JE, Chilkoti A. Sustained launch of a GLP-1 and FGF21 twin agonist from an injectable depot protects mice from weight problems and hyperglycemia. Sci Adv. 2020;6:eaaz9890.
Gilroy CA, Roberts S, Chilkoti A. Fusion of fibroblast progress issue 21 to a thermally responsive biopolymer types an injectable depot with sustained anti-diabetic motion. J Management Launch. 2018;277:154–64.
Devalliere J, Dooley Okay, Hu Y, Kelangi SS, Uygun BE, Yarmush ML. Co-delivery of a progress issue and a tissue-protective molecule utilizing elastin biopolymers accelerates wound therapeutic in diabetic mice. Biomaterials. 2017;141:149–60.
Kang HJ, Kumar S, D’Elia A, Sprint B, Nanda V, Hsia HC, Yarmush ML, Berthiaume F. Self-assembled elastin-like polypeptide fusion protein coacervates as aggressive inhibitors of superior glycation end-products improve diabetic wound therapeutic. J Management Launch. 2021;333:176–87.
Engel JE, Williams E, Williams ML, Bidwell GL third, Chade AR. Focused VEGF (vascular endothelial progress issue) remedy induces long-term renal restoration in continual Kidney Illness by way of Macrophage polarization. Hypertension. 2019;74:1113–23.
McPherson DT, Morrow C, Minehan DS, Wu J, Hunter E, Urry DW. Manufacturing and purification of a recombinant elastomeric polypeptide, G-(VPGVG)19-VPGV, from Escherichia coli. Biotechnol Prog. 1992;8:347–52.
Guda CD, Zhang X, McPherson DT, Xu J, Cherry JH, Urry DW, Daniell HJBL. Hyper expression of an environmentally pleasant artificial polymer gene. 1995, 17:745–50.
McPherson DT, Xu J, Urry DW. Product purification by reversible part transition FollowingEscherichia coliExpression of genes encoding as much as 251 repeats of the Elastomeric Pentapeptide GVGVP. Protein Exp Purif. 1996;7:51–7.
Meyer DE, Chilkoti AJB. Genetically encoded synthesis of protein-based polymers with exactly specified molecular weight and sequence by recursive directional ligation: examples from the elastin-like polypeptide system. 2002, 3 2:357–67.
McDaniel JR, MacKay JA, Quiroz FG, Chilkoti A. Recursive directional ligation by plasmid Reconstruction permits Speedy and Seamless Cloning of oligomeric genes. Biomacromolecules. 2010;11:944–52.
Tang NC, Chilkoti A. Combinatorial codon scrambling allows scalable gene synthesis and amplification of repetitive proteins. Nat Mater. 2016;15:419–24.
Dai M, Georgilis E, Goudounet G, Garbay B, Pille J, van Hest JCM, Schultze X, Garanger E, Lecommandoux S. Refining the design of Diblock Elastin-Like Polypeptides for Self-Meeting into nanoparticles. Polym (Basel). 2021;13:1470.
Mozhdehi D, Luginbuhl KM, Simon JR, Dzuricky M, Berger R, Varol HS, Huang FC, Buehne KL, Mayne NR, Weitzhandler I, et al. Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature-triggered hierarchical self-assembly. Nat Chem. 2018;10:496–505.
Rosselin M, Xiao Y, Belhomme L, Lecommandoux S, Garanger E. Increasing the Toolbox of Chemoselective Modifications of Protein-like Polymers at methionine residues. ACS Macro Lett. 2019;8:1648–53.
Pagar AD, Patil MD, Flood DT, Yoo TH, Dawson PE, Yun H. Current advances in Biocatalysis with Chemical modification and expanded amino acid alphabet. Chem Rev. 2021;121:6173–245.
Gueta O, Sheinenzon O, Azulay R, Shalit H, Strugach DS, Hadar D, Gelkop S, Milo A, Amiram M. Tuning the properties of protein-based polymers utilizing high-performance Orthogonal Translation programs for the incorporation of fragrant non-canonical amino acids. Entrance Bioeng Biotechnol. 2022;10:913057.
Costa SA, Simon JR, Amiram M, Tang L, Zauscher S, Brustad EM, Isaacs FJ, Chilkoti A. Photograph-crosslinkable unnatural amino acids allow facile synthesis of Thermoresponsive Nano- to Microgels of intrinsically disordered polypeptides. Adv Mater. 2018;30:1704878.
Jeong W-j, Sh Okay, Lim Y-b. Modular self-assembling peptide platform with a tunable thermoresponsiveness by way of a single amino acid substitution. Adv Funct Mater. 2018;28:1803114.
Bravo-Anaya LM, Garbay B, Nando-Rodriguez JLE, Carvajal Ramos F, Ibarboure E, Bathany Okay, Xia Y, Rosselgong J, Joucla G, Garanger E, Lecommandoux S. Nucleic acids complexation with cationic elastin-like polypeptides: Stoichiometry and stability of nano-assemblies. J Colloid Interface Sci. 2019;557:777–92.
Petitdemange R, Garanger E, Bataille L, Bathany Okay, Garbay B, Deming TJ, Lecommandoux S. Tuning Thermoresponsive properties of Cationic Elastin-like polypeptides by various counterions and side-chains. Bioconjug Chem. 2017;28:1403–12.
Meco E, Zheng WS, Sharma AH, Lampe KJ. Guiding oligodendrocyte precursor cell maturation with urokinase plasminogen activator-degradable elastin-like protein hydrogels. Biomacromolecules. 2020;21:4724–36.
Urry DW, Gowda DC, Parker TM, Luan CH, Reid MC, Harris CM, Pattanaik A, Harris RD. Hydrophobicity scale for proteins based mostly on inverse temperature transitions. Biopolymers. 1992;32:1243–50.
Tarakanova A, Huang W, Weiss AS, Kaplan DL, Buehler MJ. Computational sensible polymer design based mostly on elastin protein mutability. Biomaterials. 2017;127:49–60.
Cobb JS, Seale MA, Janorkar AV. Analysis of machine studying algorithms to foretell the hydrodynamic radii and transition temperatures of chemo-biologically synthesized copolymers. Comput Biol Med. 2021;128:104134.
Heyda J, Okur HI, Hladilkova J, Rembert KB, Hunn W, Yang T, Dzubiella J, Jungwirth P, Cremer PS. Guanidinium can each trigger and forestall the hydrophobic collapse of Biomacromolecules. J Am Chem Soc. 2017;139:863–70.
Ta DT, Vanella R, Nash MA. Bioorthogonal Elastin-like polypeptide scaffolds for Immunoassay Enhancement. ACS Appl Mater Interfaces. 2018;10:30147–54.
Brennan MJ, Kilbride BF, Wilker JJ, Liu JC. A bioinspired elastin-based protein for a cytocompatible underwater adhesive. Biomaterials. 2017;124:116–25.
Goetzfried MA, Vogele Okay, Muckl A, Kaiser M, Holland NB, Simmel FC, Pirzer T. Periodic operation of a dynamic DNA origami construction using the hydrophilic-hydrophobic phase-transition of stimulus-sensitive polypeptides. Small. 2019;15:e1903541.
Ge Z, Xiong Z, Zhang D, Li X, Zhang G. Distinctive part transition of Exogenous Fusion Elastin-like polypeptides within the resolution containing polyethylene glycol. Int J Mol Sci. 2019;20:3560.
Phour A, Gaur V, Banerjee A, Bhattacharyya J. Recombinant protein polymers as carriers of chemotherapeutic brokers. Adv Drug Deliv Rev. 2022;190:114544.
Jenkins IC, Milligan JJ, Chilkoti A. Genetically encoded Elastin-Like Polypeptides for Drug Supply. Adv Healthc Mater. 2021;10:e2100209.
Chief B, Baca QJ, Golan DE. Protein therapeutics: a abstract and pharmacological classification. Nat Rev Drug Discovery. 2008;7:21–39.
Conrad U, Plagmann I, Malchow S, Sack M, Floss DM, Kruglov AA, Nedospasov SA, Rose-John S, Scheller J. ELPylated anti-human TNF therapeutic single-domain antibodies for prevention of deadly septic shock. Plant Biotechnol J. 2011;9:22–31.
Costa SA, Mozhdehi D, Dzuricky MJ, Isaacs FJ, Brustad EM, Chilkoti A. Lively concentrating on of Most cancers cells by Nanobody Adorned Polypeptide Micelle with Bio-orthogonally Conjugated Drug. Nano Lett. 2019;19:247–54.
Bech EM, Martos-Maldonado MC, Wismann P, Sorensen KK, van Witteloostuijn SB, Thygesen MB, Vrang N, Jelsing J, Pedersen SL, Jensen KJ. Peptide half-life extension: Divalent, small-molecule albumin interactions direct the systemic properties of Glucagon-Like peptide 1 (GLP-1) Analogues. J Med Chem. 2017;60:7434–46.
Guo LX, Pan Q, Chen C, Lin SS, Li Y, Li XP, Chen XF, Liu L, Li WJ, Tang XF. The impact of FGF21/GLP-1 Fusion protein on glucose and lipid metebolism utilizing Diabetic mice fashions. Diabetes 2020, 69.
Martin P. Wound Therapeutic–Aiming for Excellent Pores and skin Regeneration. 1997, 276:75–81.
Wei GB, Wang ZJ, Liu RL, Zhou CC, Li EM, Shen TL, Wang XJ, Wu YH, Li XQ. A mix of hybrid polydopamine-human keratinocyte progress issue nanoparticles and sodium hyaluronate for the environment friendly prevention of postoperative belly adhesion formation. Acta Biomater. 2022;138:155–67.
Bus P, Scharpfenecker M, Van Der Wilk P, Wolterbeek R, Bruijn JA, Baelde HJ. The VEGF-A inhibitor sFLT-1 improves renal operate by decreasing endothelial activation and irritation in a mouse mannequin of sort 1 Diabetes. Diabetologia. 2017;60:1813–21.
Guo YS, Li WX, Liu SW, Jing D, Wang YF, Feng QF, Zhang KX, Xu JJ. Development of Nanocarriers based mostly on endogenous cell membrane and their utility in Nanomedicine. Chin J Chem. 2022;40:1623–40.
Bulutoglu B, Acun A, Deng SL, Mert S, Lupon E, Lellouch AG, Cetrulo CL Jr., Uygun BE, Yarmush ML. Combinatorial use of therapeutic ELP-Based mostly Micelle particles in tissue Engineering. Adv Healthc Mater. 2022;11:e2102795.
Mura S, Nicolas J, Couvreur P. Stimuli-responsive nanocarriers for drug supply. Nat Mater. 2013;12:991–1003.
Shi X, Chen D, Liu G, Zhang H, Wang X, Wu Z, Wu Y, Yu F, Xu Q. Software of elastin-like polypeptide in Tumor Remedy. Cancers (Basel). 2022;14:3683.
Wang J, Saha S, Schaal JL, Yousefpour P, Li X, Chilkoti A. Heuristics for the optimum presentation of bioactive peptides on Polypeptide Micelles. Nano Lett. 2019;19:7977–87.
Wang W, Lee C, Pastuszka M, Laurie GW, MacKay JA. Thermally-responsive loading and launch of Elastin-Like polypeptides from contact lenses. Pharmaceutics. 2019;11:221.
third GLB: Novel protein therapeutics created utilizing the Elastin-Like Polypeptide platform. 2021, 36:367–81.
Vincent MP, Navidzadeh JO, Bobbala S, Scott EA. Leveraging self-assembled nanobiomaterials for improved most cancers immunotherapy. Most cancers Cell. 2022;40:255–76.
Guo YS, Wu D, Zhang X, Zhang KX, Luo Y. Biomolecules in cell-derived extracellular vesicle chariots as warriors to restore broken tissues. Nanoscale. 2021;13:16017–33.
Li Y, Champion JA. Self-assembling nanocarriers from engineered proteins: design, functionalization, and utility for drug supply. Adv Drug Deliv Rev. 2022;189:114462.
Guo YS, Jing D, Liu SW, Yuan Q. Development of clever transferring micro/nanomotors and their purposes in biosensing and Illness remedy. Theranostics. 2023;13:2993–3020.
Piña MJ, Girotti A, Serrano S, Muñoz R, Rodríguez-Cabello JC, Arias FJ. A double security lock tumor-specific machine for Suicide gene remedy in Breast most cancers. Most cancers Lett. 2020;470:43–53.
Hajebi S, Yousefiasl S, Rahimmanesh I, Dahim A, Ahmadi S, Kadumudi FB, Rahgozar N, Amani S, Kumar A, Kamrani E et al. Genetically Engineered viral vectors and Natural-based non-viral nanocarriers for drug supply purposes. Adv Healthc Mater 2022:e2201583.
Gonzalez-Valdivieso J, Girotti A, Munoz R, Rodriguez-Cabello JC, Arias FJ. Self-assembling ELR-Based mostly nanoparticles as Sensible Drug-Supply programs Modulating Mobile Development by way of Akt. Biomacromolecules. 2019;20:1996–2007.
Pina MJ, Girotti A, Serrano S, Munoz R, Rodriguez-Cabello JC, Arias FJ. A double security lock tumor-specific machine for Suicide gene remedy in Breast most cancers. Most cancers Lett. 2020;470:43–53.
Peddi S, Roberts SK, MacKay JA. Nanotoxicology of an elastin-like polypeptide rapamycin formulation for Breast Most cancers. Biomacromolecules. 2020;21:1091–102.
Guo H, Lee C, Shah M, Janga SR, Edman MC, Klinngam W, Hamm-Alvarez SF, MacKay JA. A novel elastin-like polypeptide drug service for cyclosporine A improves tear movement in a mouse mannequin of Sjogren’s syndrome. J Management Launch. 2018;292:183–95.
Banskota S, Saha S, Bhattacharya J, Kirmani N, Yousefpour P, Dzuricky M, Zakharov N, Li X, Spasojevic I, Younger Okay, Chilkoti A. Genetically encoded Stealth nanoparticles of a Zwitterionic polypeptide-paclitaxel Conjugate have a wider therapeutic window than Abraxane in a number of Tumor fashions. Nano Lett. 2020;20:2396–409.
Hill LK, Frezzo JA, Katyal P, Hoang DM, Ben Youss Gironda Z, Xu C, Xie X, Delgado-Fukushima E, Wadghiri YZ, Montclare JK. Protein-Engineered Nanoscale micelles for dynamic (19)F magnetic resonance and therapeutic drug supply. ACS Nano. 2019;13:2969–85.
Li Y, Champion JA. Photocrosslinked, tunable protein vesicles for drug supply purposes. Adv Healthc Mater. 2021;10:e2001810.
Kelly G, Milligan JJ, Mastria EM, Kim S, Zelenetz SR, Dobbins J, Cai LY, Li X, Nair SK, Chilkoti A. Intratumoral supply of brachytherapy and immunotherapy by a thermally triggered polypeptide depot. J Management Launch. 2022;343:267–76.
Cooper BM, Iegre J, DH OD, Olwegard Halvarsson M, Spring DR. Peptides as a platform for focused therapeutics for most cancers: peptide-drug conjugates (PDCs). Chem Soc Rev. 2021;50:1480–94.
Zhu Y-S, Tang Okay, Lv J. Peptide–drug conjugate-based novel molecular drug supply system in most cancers. Traits Pharmacol Sci. 2021;42:857–69.
Bhattacharyya J, Ren XR, Mook RA, Wang J, Spasojevic I, Premont RT, Li X, Chilkoti A, Chen W. Niclosamide-conjugated polypeptide nanoparticles inhibit wnt signaling and colon Most cancers progress. Nanoscale. 2017;9:12709–17.
Yousefpour P, Ahn L, Tewksbury J, Saha S, Costa SA, Bellucci JJ, Li X, Chilkoti A. Conjugate of doxorubicin to albumin-binding peptide outperforms Aldoxorubicin. Small. 2019;15:e1804452.
Bhattacharyya J, Weitzhandler I, Ho SB, McDaniel JR, Li X, Tang L, Liu J, Dewhirst M, Chilkoti A. Encapsulating a hydrophilic chemotherapeutic into rod-like nanoparticles of a genetically encoded uneven triblock polypeptide improves its efficacy. Adv Funct Mater. 2017;27:1605421.
Ryu JS, Kratz F, Raucher D. Cell-penetrating Doxorubicin launched from Elastin-Like Polypeptide kills doxorubicin-resistant Most cancers cells in in Vitro Research. Int J Mol Sci. 2021;22:1126.
Dragojevic S, Turner L, Raucher D. Circumventing Doxorubicin Resistance utilizing elastin-like polypeptide Biopolymer-mediated drug supply. Int J Mol Sci. 2022;23:2301.
Gonzalez-Obeso C, Rodriguez-Cabello JC, Kaplan DL. Quick and reversible crosslinking of a silk elastin-like polymer. Acta Biomater. 2022;141:14–23.
Acosta S, Quintanilla-Sierra L, Mbundi L, Reboto V, Rodríguez‐Cabello JC. Elastin‐like recombinamers: deconstructing and recapitulating the performance of Extracellular Matrix proteins utilizing recombinant protein polymers. Adv Funct Mater. 2020;30:1909050.
Zhao H, Ibrahimova V, Garanger E, Lecommandoux S. Dynamic spatial formation and distribution of intrinsically disordered protein droplets in Macromolecularly crowded protocells. Angew Chem Int Ed Engl. 2020;59:11028–36.
Moysidou C-M, Barberio C, Owens RM. Advances in Engineering Human Tissue Fashions. 2021, 8: 620962.
Xing H, Lee H, Luo L, Kyriakides TR. Extracellular matrix-derived biomaterials in engineering cell operate. Biotechnol Adv. 2020;42:107421.
Salinas-Fernández S, Santos M, Alonso M, Quintanilla L, Rodríguez-Cabello JC. Genetically engineered elastin-like recombinamers with sequence-based molecular stabilization as superior bioinks for 3D bioprinting. Appl Mater At the moment. 2020;18:100500.
Hunt DR, Klett KC, Mascharak S, Wang H, Gong D, Lou J, Li X, Cai PC, Suhar RA, Co JY, et al. Engineered matrices allow the tradition of human patient-derived intestinal organoids. Adv Sci (Weinh). 2021;8:2004705.
Khalili M, Zarebkohan A, Dianat-Moghadam H, Panahi M, Andre H, Alizadeh E. Corneal endothelial cell sheet bioengineering from neural crest cell-derived adipose stem cells on novel thermo-responsive elastin-mimetic dendrimers adorned with RGD. Chem Eng J. 2022;429:132523.
Wang H, Zhu D, Paul A, Cai L, Enejder A, Yang F, Heilshorn SC. Covalently adaptable elastin-like protein – hyaluronic acid (ELP – HA) hybrid hydrogels with secondary thermoresponsive crosslinking for injectable stem cell supply. Adv Funct Mater. 2017;27:1605609.
Madl CM, LeSavage BL, Khariton M, Heilshorn SC. Neural progenitor cells alter Chromatin Group and neurotrophin expression in response to 3D Matrix Degradability. Adv Healthc Mater. 2020;9:e2000754.
Navarro RS, Huang MS, Roth JG, Hubka KM, Lengthy CM, Enejder A, Heilshorn SC. Tuning polymer hydrophilicity to manage gel mechanics and encapsulated cell morphology. Adv Healthc Mater. 2022;11:e2200011.
Ibanez-Fonseca A, Orbanic D, Arias FJ, Alonso M, Zeugolis DI, Rodriguez-Cabello JC. Affect of the Thermodynamic and Kinetic Management of Self-Meeting on the microstructure evolution of Silk-Elastin-Like Recombinamer Hydrogels. Small. 2020;16:e2001244.
Wieduwild R, Howarth M. Assembling and adorning hyaluronan hydrogels with twin protein superglues to imitate cell-cell interactions. Biomaterials. 2018;180:253–64.
Kwon H, Brown WE, Lee CA, Wang D, Paschos N, Hu JC, Athanasiou KA. Surgical and tissue engineering methods for articular cartilage and meniscus restore. Nat Rev Rheumatol. 2019;15:550–70.
Betre H, Setton LA, Meyer DE, Chilkoti A. Characterization of a genetically engineered elastin-like polypeptide for cartilaginous tissue restore. Biomacromolecules. 2002;3:910–6.
Hrabchak C, Rouleau J, Moss I, Woodhouse Okay, Akens M, Bellingham C, Keeley F, Dennis M, Yee A. Evaluation of biocompatibility and preliminary analysis of genipin cross-linked elastin-like polypeptides within the remedy of an osteochondral knee defect in rabbits. Acta Biomater. 2010;6:2108–15.
Glassman MJ, Avery RK, Khademhosseini A, Olsen BD. Toughening of Thermoresponsive arrested networks of Elastin-Like polypeptides to engineer cytocompatible tissue scaffolds. Biomacromolecules. 2016;17:415–26.
Feng Q, Gao H, Wen H, Huang H, Li Q, Liang M, Liu Y, Dong H, Cao X. Engineering the mobile mechanical microenvironment to manage stem cell chondrogenesis: insights from a microgel mannequin. Acta Biomater. 2020;113:393–406.
Koons GL, Diba M, Mikos AG. Supplies design for bone-tissue engineering. Nat Opinions Mater. 2020;5:584–603.
Li L, Eyckmans J, Chen CS. Designer biomaterials for mechanobiology. Nat Mater. 2017;16:1164–8.
Haugh MG, Vaughan TJ, Madl CM, Raftery RM, McNamara LM, O’Brien FJ, Heilshorn SC. Investigating the interaction between substrate stiffness and ligand chemistry in directing mesenchymal stem cell differentiation inside 3D macro-porous substrates. Biomaterials. 2018;171:23–33.
Zhu D, Wang H, Trinh P, Heilshorn SC, Yang F. Elastin-like protein-hyaluronic acid (ELP-HA) hydrogels with decoupled mechanical and biochemical cues for cartilage regeneration. Biomaterials. 2017;127:132–40.
Ma C, Li B, Shao B, Wu B, Chen D, Su J, Zhang H, Liu Okay. Anisotropic protein organofibers encoded with extraordinary mechanical habits for Mobile Mechanobiology Purposes. Angew Chem Int Ed Engl. 2020;59:21481–7.
Zhang J, Li B, Zuo J, Gu R, Liu B, Ma C, Li J, Liu Okay. An Engineered protein Adhesive with properties of tissue integration and managed launch for environment friendly cartilage restore. Adv Healthc Mater. 2021;10:e2100109.
Chen Z, Zhang Q, Li H, Wei Q, Zhao X, Chen F. Elastin-like polypeptide modified silk fibroin porous scaffold promotes osteochondral restore. Bioact Mater. 2021;6:589–601.
Camasao DB, Gonzalez-Perez M, Palladino S, Alonso M, Rodriguez-Cabello JC, Mantovani D. Elastin-like recombinamers in collagen-based tubular gels enhance cell-mediated reworking and viscoelastic properties. Biomater Sci. 2020;8:3536–48.
Dos Santos BP, Garbay B, Fenelon M, Rosselin M, Garanger E, Lecommandoux S, Oliveira H, Amedee J. Improvement of a cell-free and progress factor-free hydrogel able to inducing angiogenesis and innervation after subcutaneous implantation. Acta Biomater. 2019;99:154–67.
Guo C, Li C, Vu HV, Hanna P, Lechtig A, Qiu Y, Mu X, Ling S, Nazarian A, Lin SJ, Kaplan DL. Thermoplastic moulding of regenerated silk. Nat Mater. 2020;19:102–8.
Katyal P, Hettinghouse A, Meleties M, Hasan S, Chen C, Cui M, Solar G, Menon R, Lin B, Regatte R, et al. Injectable recombinant block polymer gel for sustained supply of therapeutic protein in submit traumatic osteoarthritis. Biomaterials. 2022;281:121370.
Zhang F, King MW. Immunomodulation methods for the profitable regeneration of a tissue-Engineered Vascular Graft. 2022, 11:2200045.
Xiao L, Wang Z, Solar Y, Li B, Wu B, Ma C, Petrovskii VS, Gu X, Chen D, Potemkin II, et al. An Synthetic phase-transitional underwater bioglue with strong and switchable adhesion efficiency. Angew Chem Int Ed Engl. 2021;60:12082–9.
Ma C, Solar J, Li B, Feng Y, Solar Y, Xiang L, Wu B, Xiao L, Liu B, Petrovskii VS, et al. Extremely-strong bio-glue from genetically engineered polypeptides. Nat Commun. 2021;12:3613.
Girotti A, Gonzalez-Valdivieso J, Santos M, Martin L, Arias FJ. Purposeful characterization of an enzymatically degradable multi-bioactive elastin-like recombinamer. Int J Biol Macromol. 2020;164:1640–8.
Gonzalez-Perez F, Ibanez-Fonseca A, Alonso M, Rodriguez-Cabello JC. Combining tunable proteolytic sequences and a VEGF-mimetic peptide for the spatiotemporal management of angiogenesis inside Elastin-Like Recombinamer scaffolds. Acta Biomater. 2021;130:149–60.
Piroth M, Gorski DJ, Hundhausen C, Petz A, Gorressen S, Semmler D, Zabri H, Hartwig S, Lehr S, Kelm M, et al. Hyaluronan synthase 3 is protecting after cardiac ischemia-reperfusion by preserving the T cell response. Matrix Biol. 2022;112:116–31.
Contessotto P, Orbanic D, Da Costa M, Jin C, Owens P, Chantepie S, Chinello C, Newell J, Magni F, Papy-Garcia D, et al. Elastin-like recombinamers-based hydrogel modulates post-ischemic reworking in a non-transmural Myocardial Infarction in sheep. Sci Transl Med. 2021;13:eaaz5380.
Marsico G, Jin C, Abbah SA, Brauchle EM, Thomas D, Rebelo AL, Orbanic D, Chantepie S, Contessotto P, Papy-Garcia D, et al. Elastin-like hydrogel stimulates angiogenesis in a extreme mannequin of important limb ischemia (CLI): an perception into the glyco-host response. Biomaterials. 2021;269:120641.
Ibanez-Fonseca A, Rico A, Preciado S, Gonzalez-Perez F, Muntion S, Garcia-Brinon J, Garcia-Macias MC, Rodriguez-Cabello JC, Pericacho M, Alonso M, Sanchez-Guijo F. Mesenchymal stromal cells mixed with Elastin-Like recombinamers improve angiogenesis in vivo after Hindlimb Ischemia. Entrance Bioeng Biotechnol. 2022;10:918602.
Roberts S, Harmon TS, Schaal JL, Miao V, Li KJ, Hunt A, Wen Y, Oas TG, Collier JH, Pappu RV, Chilkoti A. Injectable tissue integrating networks from recombinant polypeptides with tunable order. Nat Mater. 2018;17:1154–63.
Kojima H, Yasuchika Okay, Fukumitsu Okay, Ishii T, Ogiso S, Miyauchi Y, Yamaoka R, Kawai T, Katayama H, Yoshitoshi-Uebayashi EY et al. Institution of sensible recellularized liver graft for blood perfusion utilizing main rat hepatocytes and liver sinusoidal endothelial cells. 2018, 18:1351–9.
Devalliere J, Chen Y, Dooley Okay, Yarmush ML, Uygun BE. Bettering useful re-endothelialization of acellular liver scaffold utilizing REDV cell-binding area. Acta Biomater. 2018;78:151–64.
Solar M, Peng D, Hao H, Hu J, Wang D, Wang Okay, Liu J, Guo X, Wei Y, Gao W. Thermally triggered in situ Meeting of Gold nanoparticles for Most cancers Multimodal Imaging and Photothermal Remedy. ACS Appl Mater Interfaces. 2017;9:10453–60.
Alvisi N, Gutiérrez-Mejía FA, Lokker M, Lin Y-T, de Jong AM, van Delft F, de Vries R. Self-assembly of elastin-like polypeptide brushes on silica surfaces and nanoparticles. Biomacromolecules. 2021;22:1966–79.
[ad_2]